Cooper Kupp dove and extended the ball towards the first-down marker, hoping to extend a Seahawks drive late in the fourth quarter, but he was ruled just short on fourth down. That turnover on downs gave the 49ers the ball back to run out the clock on a 32-29 victory. And though the game came down to a matter of inches at the end, it was several big mistakes earlier in the game that had the Seahawks trying to claw their way back at the end.

Here are five rapid reactions to Sunday's loss to the 49ers:

1. Turnovers have become a real issue for the Seahawks.

The Seahawks' first loss of the season, which came in Week 3 at Washington, wasn't the result of Seattle being outplayed on a down-to-down basis, but because of three turnovers that led to 21 points for their opponent. Two weeks later, it was more of the same for the Seahawks as multiple turnovers cost the Seahawks in a big way, with the 49ers scoring 21 points off Seahawks turnovers, all of which coming in the first half.

For the second week in a row, Sam Darnold was intercepted on Seattle's first possession, and the 49ers turned that short field into a Mike Evans touchdown reception. In the second quarter, Emanuel Wilson lost a fumble, giving the 49ers another possession that started in the red zone and led to a one-play 49ers possession, with Christian McCaffrey scoring on an 11-yard run. To cap off a rough first half, George Holani fumbled near the goal line with just 13 seconds remaining, and the 49ers recovered in the end zone. Holani also fumbled with no one near him after a catch earlier in the game and while he was able to recover, he turned what might have been a touchdown into a 7-yard gain, and the Seahawks ended up settling for a field goal. The Seahawks quickly had a fourth turnover, another Darnold interception two plays into the second half, but the defense was able to get a quick stop and a missed field goal allowed Seattle to escape any damage.

With the Chargers getting a field goal off a Darnold interception last week, that makes 45 points off turnovers for Seattle's opponents, including two defensive scores, over the past three games.

2. The Seahawks defense was so much better than the scoreboard indicated.

The final score would suggest a pretty good day for the 49ers offense, and while Brock Purdy, Mike Evans and company deserve plenty of credit for making some good things happen, the Seahawks defense was much better than what an opponent scoring 32 points would indicate.

As detailed above, the 49ers got 21 points off of turnovers, with one defensive touchdown and two touchdown drives that started in the red zone.

Overall, the 49ers were held to 269 yards, 14 first downs, went 4 for 12 on third down, and averaged 4.8 yards per play, all very solid defensive numbers facing one of the league's most efficient offenses. And only 11 of those 32 points came off drives that did not begin with a Seahawks turnover to give the 49ers great possession.

Add to that three sacks, the first three on Purdy all season, and multiple takeaways, and it was a very solid defensive outing despite the final score.

3. "Mighty" Nehemiah Pritchett lived up to his nickname.

When Nehemiah Pritchett was a young child growing up in Jackson, Alabama, some of his cousins, deciding Nehemiah was too much of a mouthful, gave him the nickname, Mighty. That name stuck with Pritchett throughout his childhood and into his NFL career, and on Sunday, the third-year cornerback lived up to the "Mighty" moniker.

Pritchett, who last season made his mark on special teams, has taken on a bigger role on defense this year, but he's still a key special teamer, and he came up with a big play early in Sunday's game. As 49ers returner Jacob Cowing settled under a high, wobbling Michael Dickson punt, Pritchett, one of Seattle's gunners, slowed down just enough to make sure he didn't get to Cowing early, then blasted the returner with a hard, legal hit to knock the ball loose, with Eric Saubert recovering for a turnover that set up an eventual Emanuel Wilson touchdown run. Cowing mishandled the punt and it was already going through his hands as Pritchett hit him, so it was officially a muffed punt with no forced fumble, but if not for Pritchett's well-timed hit, Cowing may have recovered his own bobble.

In the third quarter, with the Seahawks trailing after too many turnovers of their own, Pritchett came up with another big play, intercepting Brock Purdy -- just the second thrown by the 49ers QB this season -- giving the Seahawks another short field that would lead to a Jaxon Smith-Njigba touchdown reception.

4. Byron Murphy II did what four other NFL teams could not… twice.

Through four games, one of the most remarkable stats about the 49ers' 4-0 start was the fact that quarterback Brock Purdy had not been sacked once. Some of that has to do with good pass protection, but it is also because Purdy is incredibly elusive in the pocket. And though Purdy was able to make things happen with his legs at times on Sunday, defensive tackle Byron Murphy II was able to get him down twice, giving him his second and third sacks of the season. The Seahawks added a third sack on Purdy when Ernest Jones IV chased him down behind the line of scrimmage on a scramble.

Those two sacks were part of what was a very impressive game for Murphy, who had six tackles and three tackles for loss, including a run stuff for a one-yard loss to get a third-and-one stop late in the game.

5. Jason Myers had a great day, but unfortunately didn't get to attempt one more kick.

In addition to getting a takeaway on special teams, the Seahawks also scored a lot of points in that phase of the game, with Jason Myers going 5 for 5 on field goal attempts, all from 40 yards or longer. The Seahawks did not, however, quite get in position for Myers to attempt a sixth field goal to potentially tie the game late.