Hired on February 22, 2022, to be the team's defensive pass game coordinator/defensive backs coach, Karl Scott enters the 2023 season in a new role, now the team's defensive pass game coordinator/senior defensive assistant. Scott served one season (2021) as the defensive backs coach with the Vikings in his inaugural season in the NFL. Prior to Minnesota, he served as Alabama's cornerbacks coach from 2018-20.

Hired on February 22, 2022, to be the team's defensive pass game coordinator/defensive backs coach, Karl Scott enters the 2023 season in a new role, now the team's defensive pass game coordinator/senior defensive assistant. Scott served one season (2021) as the defensive backs coach with the Vikings in his inaugural season in the NFL. Prior to Minnesota, he served as Alabama's cornerbacks coach from 2018-20.

Last season, Scott helped lead the rapid development of rookie cornerbacks Coby Bryant, Tariq Woolen, and first-year starter Michael Jackson. Woolen set a rookie franchise record and tied for first in the NFL with six interceptions while being named to the NFC Pro Bowl Games roster. He become the first Seattle defensive rookie to be named to the Pro Bowl since 2005 (LB Lofa Tatupu). Woolen was also the first rookie since 2000 and first player since 2016 (Marcus Peters) with at least 15 passes defensed, six interceptions and three fumble recoveries in a single season. Quandre Diggs was named to the NFC Pro Bowl Games for the third-consecutive season, while registering four interceptions and became the only player in the NFL to record at least three interceptions in each of the past six seasons (2017-22). 

Under Scott's guidance, Seattle made improvements in the passing game in 2022, including completions allowed per game (31st in NFL in 2021 to 10th in 2022), Passing Yards Allowed Per Game (31st to 13th), Passing 1st Downs Allowed (32nd to 15th). 

Scott played a big role in helping Harrison Smith garner his sixth Pro Bowl selection in 2021. Under Scott's leadership, Smith also tied his career high in sacks with 3.0, while registering 114 tackles, seven passes defensed and one interception. With Xavier Woods playing on a one-year deal, Scott assisted Woods in revitalizing his career, tying for the team-lead in interceptions with three and being the only Viking to play 100% of the team's snaps in 2021.

In 2020, Scott helped Alabama to a National Championship as the defense allowed just 19.4 points per game, ranking 13th in the nation. The Crimson Tide ranked third in the SEC in pass defense and opposing quarterbacks completed just 58.1% of passes, throwing 12 interceptions. Alabama finished the 2020 season leading the SEC in pass efficiency defense and scoring defense. Under Scott, CB Patrick Surtain II led the SEC with 13 passes defended and 12 pass breakups, en route to unanimous All-America honors and being drafted in the first round (ninth overall).

Scott tutored 2020 second round NFL draftee (51st overall) Trevon Diggs on one side and Surtain II on the other while senior Shyheim Carter manned the star position in 2019. Diggs had three interceptions, 37 tackles and eight pass breakups. Surtain II made 42 stops with two interceptions and two forced fumbles, while Carter added 43 tackles and seven pass breakups. Under Scott's direction, Alabama ranked fourth nationally and first in the SEC in pass efficiency defense (109.75), finishing with 17 interceptions and 50 pass breakups.

 In 2018, Scott was charged with replacing five starters in the secondary from the Tide's 2017 National Championship team with Minkah Fitzpatrick, Ronnie Harrison, Anthony Averett, Levi Wallace and Tony Brown all off to the NFL.

The completely overhauled secondary turned in a quality season, ranking 26th nationally in pass efficiency defense (115.79) and 33rd in pass yards allowed (198.3). Led by consensus All-America safety Deionte Thompson, the Tide allowed just 22 passing touchdowns while intercepting 15 passes. Thompson was second on the team in tackles with 79 while picking off two passes and breaking up six more. Safety Xavier McKinney also excelled at safety with 73 stops, six tackles for loss, 3.0 sacks and two inteceptions. Surtain II earned freshman All-America honors on the opposite side with 37 tackles and an interceptions while Carter played the nickel and added 44 tackles and two inteceptions.

Scott spent the 2016-17 seasons as the secondary coach at Texas Tech before being named the defensive coordinator at Louisiana-Lafayette in late December of 2017. In 2017, his unit posted an impressive turnaround, helping produce 29 turnovers, including 14 inteceptions. He mentored All-Big 12 selections in Jah'Shawn Johnson and Justus Parker.

Prior to his time at Texas Tech, Scott spent one season (2015) as the safeties coach at Louisiana Tech under head coach Skip Holtz. He helped the Bulldogs to a 9-4 record and a second-place finish in the Western Division of Conference USA. Louisiana Tech defeated Arkansas State in the New Orleans Bowl as the Bulldogs finished eighth nationally in defensive touchdowns after forcing 22 turnovers, including 13 interceptions.

Scott worked at Southeastern Louisiana for three years, serving as the defensive coordinator in 2014 and linebackers coach in 2012-13. During his tenure with the Lions, he helped lead the program to back-to-back Southland Conference Championships (2013-14) and two NCAA Football Championship Division playoff appearances.

His 2014 defense at Southeastern led the Southland Conference in total defense while ranking seventh in the FCS. The Lions also led the nation in pass efficiency defense (94.3), and ranked fifth in red zone defense, eighth in scoring defense (17.7 ppg) and 11th in turnovers (28).

Isiah Corbett and Harlan Miller were two mainstays on Scott's defense at Southeastern Louisiana, both earning All-America honors in 2014, while seven other defenders – Denzel Thompson, Jacob Newman, Tyler Stoddard, A.J. Bowen, Drew Misita, Jordan Batiste and Micah Eugene – joined the pair on the All-Southland Conference teams.

Scott's linebackers unit was a key factor in Southeastern's 2013 Southland Conference championship campaign. His corps benefited from the emergence of Cqulin Hubert, who was named Southland Defensive Player of the Year after recording a team-leading 90 tackles, including 11 tackles for loss.

Before his time at Southeastern Louisiana, Scott served as recruiting coordinator/defensive backs/linebackers coach for four years at Tusculum College from 2008-11.

He made an immediate impact at Tusculum, as he mentored two all-conference selections in Justin Scott and Jarvis Littlejohn. Scott collected all-region honors following the 2008 season, establishing new school records for single-season (22) and career (51) tackles for loss while finishing the season with 113 tackles and 277 for his career.

Scott's coaching career began at Delta State as a graduate assistant in 2007. In his lone season at DSU, he helped lead the Statesman to a 10-2 record, a no. 10 final national ranking, Gulf South Conference championship and NCAA Division II playoff appearance.

A native of Houston, Scott played at McMurry University in Abilene, Texas, where he earned his degree in exercise and sports studies in 2007. Scott and his wife Taron have two daughters, Kina Bailey and Kari Mae.